National Institute of Malaria Research

 

+91-11-25307201                      director@mrcindia.org

NIMR Field Unit: Raipur (Chhattishgarh)

 

Research Staff

Dr  GDP Dutta, Research Scientist, Officer-in-charge

Dr Raju Ranjha, Scientist B

Mr MP Singh, Research Assistant

Mr BP Singh, Lab. Technician

Mr Neeraj Trivedi, Technician

Ms. Indira Katiyar, Lab. Technician

 

Ongoing Research Projects:

1. Impact of insecticide resistance in malaria vectors on the effectiveness of combination of indoor residual spraying (IRS) and long-lasting insecticidal nets (LNs) in India: a multidisciplinary approach

2. Large-scale (Phase III) evaluation of efficacy, fabric integrity and community  acceptability of Olyset Plus long-lasting insecticidal nets compared with Olyset Net in India

3. A longitudinal study on the bio-efficacy, fabric integrity and survivorship of field distributed long-lasting insecticidal nets by the state for malaria control in different districts of Chhattisgarh state

4. Monitoring of insecticide resistance in malaria vector Anopheles culicifacies in different districts of Chhattisgarh

5. Monitoring of therapeutic efficacy of anti-malarials in India

6. Micro-mapping of G6PD deficiency among the tribals of India and its importance for antimalarial therapy

 

Recent Research Publications

Dykes CL, Kushwah RB, Das MK, Sharma SN, Bhatt RM, Veer V, Agrawal OP, Adak T, Singh OP. Knockdown resistance (kdr) mutations in Indian Anopheles culicifacies populations. Parasit Vectors. 2015 Jun 18;8:333. doi: 10.1186/s13071-015-0946-7.

Gupta P, Singh R, Khan H, Raza A, Yadavendu V, Bhatt RM, Singh V. Genetic profiling of the Plasmodium falciparum population using antigenic molecular markers. ScientificWorldJournal. 2014;2014:140867. doi: 10.1155/2014/140867. Epub 2014 Oct 22.

Elamathi N, Barik TK, Verma V, Velamuri PS, Bhatt RM, Sharma SK, Raghavendra K. Standardization of a bottle assay--an indigenous method for laboratory and field monitoring of insecticide resistance and comparison with WHO adult susceptibility test. Parasitol Res. 2014 Oct;113(10):3859-66.

Singh R, Singh DP, Gupta R, Savargaonkar D, Singh OP, Nanda N, Bhatt RM, Valecha N. Comparison of three PCR-based assays for the non-invasive diagnosis of malaria: detection of Plasmodium parasites in blood and saliva. Eur J Clin Microbiol Infect Dis. 2014 Sep;33(9):1631-9. doi: 10.1007/s10096-014-2121-z. Epub 2014 May 5.

Mishra N, Singh JP, Srivastava B, Arora U, Shah NK, Ghosh SK, Bhatt RM, Sharma SK, Das MK, Kumar A, Anvikar AR, Kaitholia K, Gupta R, Sonal GS, Dhariwal AC, Valecha N. Monitoring antimalarial drug resistance in India via sentinel sites: outcomes and risk factors for treatment failure, 2009-2010. Bull World Health Organ. 2012 Dec 1;90(12):895-904. doi: 10.2471/BLT.12.109124. Epub 2012 Oct 31.

Kumar N, Pande V, Bhatt RM, Shah NK, Mishra N, Srivastava B, Valecha N, Anvikar AR. Genetic deletion of HRP2 and HRP3 in Indian Plasmodium falciparum population and false negative malaria rapid diagnostic test. Acta Trop. 2013 Jan;125(1):119-21. doi: 10.1016/j.actatropica.2012.09.015. Epub 2012 Oct 3.

Nanda N, Bhatt RM, Sharma SN, Rana PK, Kar NP, Sharma A, Adak T. Prevalence and incrimination of Anopheles fluviatilis species S (Diptera: Culicidae) in a malaria endemic forest area of Chhattisgarh state, central India. Parasit Vectors. 2012 Sep 28;5:215. doi: 10.1186/1756-3305-5-215. PubMed PMID: 23021620;

Bhatt RM, Sharma SN, Uragayala S, Dash AP, Kamaraju R. Effectiveness and durability of Interceptor® long-lasting insecticidal nets in a malaria endemic area of central India. Malar J. 2012 Jun 10;11:189. doi: 10.1186/1475-2875-11-189.

Anvikar AR, Sharma B, Sharma SK, Ghosh SK, Bhatt RM, Kumar A, Mohanty SS, Pillai CR, Dash AP, Valecha N. In vitro assessment of drug resistance in Plasmodium falciparum in five States of India. Indian J Med Res. 2012 Apr;135(4):494-9.

Bhatt RM, Sharma SN, Barik TK, Raghavendra K. Status of insecticide resistance in malaria vector, Anopheles culicifacies in Chhattisgarh state, India. J Vector Borne Dis. 2012 Mar;49(1):36-8.

Mallick PK, Joshi H, Valecha N, Sharma SK, Eapen A, Bhatt RM, Srivastava HC,  Sutton PL, Dash AP, Bhasin VK. Mutant pfcrt "SVMNT" haplotype and wild type pfmdr1 "N86" are endemic in Plasmodium vivax dominated areas of India under high  chloroquine exposure. Malar J. 2012 Jan 11;11:16. doi: 10.1186/1475-2875-11-16.

Prajapati SK, Joshi H, Shalini S, Patarroyo MA, Suwanarusk R, Kumar A, Sharma SK, Eapen A, Dev V, Bhatt RM, Valecha N, Nosten F, Rizvi MA, Dash AP. Plasmodium  vivax lineages: geographical distribution, tandem repeat polymorphism, and phylogenetic relationship. Malar J. 2011 Dec 19;10:374. doi: 10.1186/1475-2875-10-374.

Raghavendra K, Barik TK, Bhatt RM, Srivastava HC, Sreehari U, Dash AP. Evaluation of the pyrrole insecticide chlorfenapyr for the control of Culex quinquefasciatus Say. Acta Trop. 2011 Apr;118(1):50-5. doi: 10.1016/j.actatropica.2011.02.001. Epub 2011 Feb 17. PubMed PMID: 21315680.

Raghavendra K, Barik TK, Sharma P, Bhatt RM, Srivastava HC, Sreehari U, Dash  AP. Chlorfenapyr: a new insecticide with novel mode of action can control pyrethroid resistant malaria vectors. Malar J. 2011 Jan 25;10:16. doi: 10.1186/1475-2875-10-16.

Singh OP, Dykes CL, Das MK, Pradhan S, Bhatt RM, Agrawal OP, Adak T. Presence of two alternative kdr-like mutations, L1014F and L1014S, and a novel mutation, V1010L, in the voltage gated Na+ channel of Anopheles culicifacies from Orissa, India. Malar J. 2010 May 28;9:146. doi: 10.1186/1475-2875-9-146. 103(7):653-7.

 

Contact Info

Dr  GDP Dutta, Reesearch Scientist  and Officer-in Charge

National Institute of Malaria Research

Field Unit, RLTRI Campus, Lalpur

Raipur 492015, Chhattisgarh

T:+91 771 6542798; T/F: +91 771 2411281

Mobile: 9425209652

 

 

Find us on Google Map

Copyright ©2015, National Institute of Malaria Research